A Computer Animated Hand (1972)

A Computer Animated Hand is a 1972 American computer-animated film produced by Edwin Catmull and Fred Parke. Produced during Catmull's tenure at the University of Utah, the short was created for a graduate course project. After creating a model of Catmull's left hand, 350 triangles and polygons were drawn in ink on the model. The model was digitized and laboriously animated in a three-dimensional animation program that Catmull wrote.

More at Wikipedia.